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The Power of Prebiotic
Technology for Your Skin



At Sanex, we share your commitment to health.


Products with prebiotic technology inhibit pathogens in the epithelial barrier, while promoting the growth of beneficial microorganisms.


The power of
prebiotic technology

 

 

The power of prebiotic technology

 

As you know, the skin microbiome hosts a vast array of beneficial microorganisms that maintain skin health and protect it from pathogens. Therefore, preventing its disruption by using prebiotic products is essential.

Our extensive experience at Sanex has allowed us to unlock the unique benefits our products offer. This expertise led us to develop our prebiotic technology, combining prebiotic and postbiotic ingredients to deliver the same type of innovative skincare solutions we've pioneered for the last 40 years.

Below, you can explore the clinical studies demonstrating the benefits of Sanex Expert Skin Health with Prebiotic Complex.


OBJECTIVE

 

 

 

Evaluate the effectiveness of prebiotic technology on:

  • – S. aureus and E. coli (associated with infections)
  • – C. striatum (associated with odour)
  • – S. epidermidis (beneficial skin bacteria)

PREBIOTIC TECHNOLOGY

 

 

Prebiotic effect of inulin on the epithelial microbiota





Inulin significantly inhibits the growth of pathogens (E. coli, C. striatum, S. aureus) and maintains the growth of S. epidermidis in vitro.

This study is presented for educational purposes only; it was not conducted with our Sanex products and their composition may differ from that of the products tested.

 
Gráfico de efecto prebiótico de la inulina sobre la microbiota epitelial
 

 

Effect of 2-butyloctanol on C. striatum, a bacterium that causes bad odour




2-Butyloctanol significantly inhibits the growth of C. striatum at concentrations of 0.64%, 2.56%, and 5.12%.

This study is presented for educational purposes only; it was not conducted using our Sanex products and their composition may differ from that of the products tested.

 
Gráfico de bacteria causante del mal olor
 

 

Prebiotic effect of the biomimetic blend on skin bacteria

 

The postbiotic blend inhibits the growth of E. coli and C. striatum and significantly promotes the growth of beneficial bacteria in vitro.

 
Gráfico del efecto prebiótico de la mezcla biomímica sobre las bacterias de la piel
 

Sanex Natural Prebiotics body wash shows benefits during body cleansing

 

Washing with prebiotic technology demonstrated inhibition of the growth of C. striatum (b), while maintaining the levels of S. epidermidis (a).

 

The ratio of beneficial to undesirable bacteria increased significantly (p = 0.03) (c).

Benefit graph in body washing (log10 cfu/ml)
Benefit graph in body washing (log10 cfu/ml)

Benefit chart in C. striatum body wash

Prebiotic technology: significant improvement in the skin barrier

 

The gel with prebiotic technology showed an improvement in the skin barrier compared with the placebo.

Tecnología Placebo Body Wash

Placebo Body Wash

Tecnología Placebo Body Wash

Test Body Wash

Tecnología Placebo Body Lotion

Placebo Body Lotion

Tecnología Test Body Lotion

Test Body Lotion

Rojo: Rodamina B; Azul: DAPI.



Li M, Fan A, Mao J, Soliman N, Shahani K, Morgan A, et al. The Prebiotic Effect of Triple Biotic Technology on Skin Health. Journal of Cosmetics, Dermatological Sciences and Applications. 2021;11(4):304-319.


OBJECTIVE

 

Conduct a multi-omics approach to decipher the impact of skincare products containing prebiotics/postbiotics on the skin microbiome and metabolome.

 

Analysis of the effects of prebiotic products using 16S rRNA Gene Sequencing and Comparative Metagenomics

 

The prebiotic group demonstrated a significant reduction in opportunistic pathogens and an increase in commensal microorganisms, together with an enrichment of bacterial sugar degradation pathways.

 
 
 
 

Key associations: bacteria, metabolites and skin hydration




Correlation analysis revealed associations between specific bacteria, metabolites and improved skin hydration.

 

The results support the hypothesis that prebiotics/postbiotics improve skin hydration through modulation of the skin microbiome, metabolic pathways and the metabolome.