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le soin de la peau

The Power of Technology
Prebiotics for Your Skin



At Sanex, we share your commitment to health.

 


Formulated with fewer ingredients, products in the Sanex Zero% range boost skin hydration while minimising the risk of irritation.


Products with fewer chemicals
suitable for all skin types

 

 

A close-up view showing clean, wet skin with water droplets next to a fresh green leaf or plant with water drops on it, surrounded by soft green bokeh.

At Sanex, we believe in caring for both your skin and the environment. That’s why we’ve created a range of shower gels for sensitive skin that are largely biodegradable. Containing 99% biodegradable ingredients, these shower gels are formulated with 0% sulphates (including SLS), 0% colourants and 0% microplastics, helping to minimise the risk of skin irritation.

 


OBJECTIVE

 

To demonstrate efficacy in preventing lipid peroxidation of the skin and in eliminating/reducing its by-products.


STUDY DESIGN


Skin peroxidation in an ozone chamber

 

Exposure to 100 ppb ozone for 1 hour to induce MDA formation

Washing and rinsing

  1. Water (100 ml/s) for 2–3 s
  2. 200 μl of experimental sample for 75 s
  3. Water for 15 s

MDA extraction and measurement

  1. 500 μl ethanol and rub with a glass rod for 60 s (×2)
  2. Sample centrifugation
  3. Chemical analysis

A Pig skin obtained from an abattoir was used (Animals Technology, Inc.). MDA: methylenedianiline.

 


RESULTS


The sulphate-free cleansing gel generated lower levels of MDA (p<0.05).

A bar chart measuring $\text{MDA}$ concentration ($\mu\text{M}$) comparing two Sanex product formulations

The sulphate-free cleansing gel provides stronger protection

 

When the skin was exposed to ozone after washing, lower levels of lipid oxidation were observed with the sulphate-free Sanex cleansing gel (p<0.05).

A bar chart measuring $\text{MDA}$ concentration ($\mu\text{M}$) comparing two Sanex product formulations

CONCLUSION

 

Sulphate-free Sanex more effectively eliminated free radical by-products that damage the skin and prevented lipid oxidation when the skin was exposed to ozone or pollution.

 

Fan A. Anti-Pollution Benefits of Sanex Sulfate Free Zero Anti-Pollution Shower Gel. Colgate-Palmolive Global Technology Center (2020). Data on file.