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le soin de la peau

The Power of Technology
Prebiotics for Your Skin

At Sanex, we share your commitment to health.

 

Formulated with fewer ingredients, products in the Sanex Zero% range boost skin hydration while minimising the risk of irritation.

Caring for Atopic-Prone Skin

 

 

A close-up of a person's hand applying a smooth layer of white lotion or moisturizer onto their upper arm against a neutral beige background.

Atopic-prone skin has a compromised skin barrier. This barrier becomes porous and loses its protective function. It is no longer able to retain the water naturally present in the skin and cannot protect against external aggressors.

That’s why, at Sanex, we developed Atopiderm – a product that combines prebiotic technology with skin-identical lipids to help soothe itchiness and dryness through hydration.

Below, you’ll find information about the studies demonstrating the benefits of Sanex Atopiderm for atopic-prone skin.

 

OBJECTIVE

 

To evaluate the efficacy of a shower gel and lotion containing skin-identical lipids and emollients in improving dry skin in subjects with a history of atopic conditions.

DOWNLOAD PDF ARTICLE (701 KB)

STUDY DESIGN

The shower gel improves skin barrier function after 4 weeks of use, including in subjects with atopic-prone skin

TEWL analysis showed a significant reduction in mean transepidermal water loss, from 15.50 g/h/m² at baseline to 11.11 g/h/m² at Week 4 (P ≤ 0.05), and to 8.24 g/h/m² at Week 6.

Mean TEWL (g/h/m²)

A bar chart showing a decrease in Mean TEWL ($\text{g/h/m}^2$) over time, with data points for Week 0, Week 4 (marked with an asterisk), and Week 6 (marked with a hash symbol).

The shower gel improves the skin barrier function after 4 weeks of use, even in individuals with atopic skin

TEWL analysis showed a significant reduction in the mean level of water loss, from 15.50 g/h/m² to 11.11 g/h/m² at Week 4 (P ≤ 0.05), and to 8.24 g/h/m² at Week 6.

A microscopic or close-up view showing dry, cracked, and flaking skin texture with pronounced white lines and scaling.

Week 0

A microscopic or close-up view showing skin undergoing hydration, with slightly reduced cracking and improved surface texture.

Week 4

A microscopic or close-up view showing hydrated, smooth, and healthy skin texture with minimal flaking or surface lines.

week 6

Symptoms of AD improve significantly with these products

Dermatologist assessments of patients demonstrated a significant improvement in AD-related symptoms following the use of these products.

A bar chart displaying mean scores (VAS 0–10) across weeks 0, 4, and 6 for various skin conditions, showing noticeable reductions over time

Berardesca E, Mortillo S, Cameli N, Ardigo M, Mariano M. Efficacy of a shower cream and a lotion with skin-identical lipids in healthy subjects with atopic dry skin. J Cosmet Dermatol. 2018 Jun;17(3):477-483.

OBJECTIVE

 

To evaluate the prebiotic effect of Sanex Atopiderm shower gel with triple-biotics technology.

 

DOWNLOAD PDF ARTICLE (205 KB)

A growth inhibition assay was conducted to determine whether the complete formulation inhibits or promotes the growth of skin bacteria.

 

Study Microbiota

  • Staphylococcus epidermidis
  • Staphylococcus aureus

Study Groups

  • Sanex Atopiderm
  • Sanex (placebo)
  • La Roche Posay (reference)

No increase was observed in S. aureus growth or in the S. epidermidis/S. aureus ratio compared with placebo and the reference sample.

A bar chart titled "S. aureus" measuring bacteria load ($\text{CFU/ml}$) across three groups
A bar chart titled "S. epidermidis / S. aureus" measuring the ratio between the two bacterial species across three groups